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Healthy Home Economist / Archives / Detoxification / High Dose Vitamin C “Flush”: Safe or Risky?

High Dose Vitamin C “Flush”: Safe or Risky?

by Sarah Pope / Affiliate Links ✔

Table of Contents[Hide][Show]
  • How to Take High Dose Vitamin C Orally (Vitamin C Flush)
  • How Much Ascorbic Acid is Needed?
  • Ascorbate Cleanse Benefits?
  • Vitamin C Flush Risks+−
    • Whole Vitamin C Compared to Ascorbic Acid
    • GMO Vitamin C
  • Health Risks from High Dose Ascorbic Acid
  • Alternatives to a Vitamin C Flush
  • Therapeutic Uses for High Dose Vitamin C+−
    • Cancer Therapy
    • Removal of Amalgams

Pros and cons of Vitamin C flush, “ascorbic acid cleanse” and why it is not a safe practice for regular use, especially for children.

High dose Vitamin C flush mixed in glass of water

Ever since Linus Pauling popularized the practice of taking high dose vitamin C orally to combat the common cold in the early 1970s, some within the alternative health community have enthusiastically touted the benefits of a “vitamin C flush” or ascorbate cleanse.

I’ve always been skeptical of taking large doses of isolated vitamins for any purpose. Using nutrients like drugs seems a short-sighted approach to healing. I am particularly dubious of large doses of ascorbic acid separated from the beneficial flavonoids and other co-factors present in whole food forms of Vitamin C.

How to Take High Dose Vitamin C Orally (Vitamin C Flush)

The primary goal of flushing the body with high doses of vitamin C is to achieve rapid detoxification or speed recovery from an illness.

Note that it is quite different from a niacin flush, which also assists in cleansing. One alternative practitioner once recommended a high dose vitamin C when my toddler had a fever.

I didn’t take this advice for reasons covered a bit later in the article.

Here’s the process in a nutshell:

  1. In the morning ideally, on an empty stomach, take 1000 milligrams of ascorbic acid powder mixed into 4 ounces of filtered water. Buffered ascorbate powder, which is ascorbic acid bound to minerals like calcium, magnesium, or potassium, is another option. If you have a sensitive stomach, buffered ascorbic acid is the better choice.
  2. Repeat every half hour until you make a mad dash for the bathroom with an urgent case of watery diarrhea. A loose stool is not sufficient. Keep going until a large amount of liquid is rapidly evacuated from the body. At that point, do not take any more ascorbic acid that day.
  3. Drink plenty of filtered water, homemade electrolyte beverage, and bone broth to prevent dehydration.
  4. Optional step. If desired, cut the dosage by at least half and continue to take every four hours for the next 1-2 days to continue the detoxification process. The goal is to maintain loose, but not watery stools. If stools are too loose, cut the dose back further before continuing.
  5. Some practitioners suggest doing a flush once a week for 3-6 months.

How Much Ascorbic Acid is Needed?

The average person requires 4-8 1000 mg doses of ascorbic acid or ascorbate powder for the initial bathroom run to occur.

See what I mean about high-dose vitamin C being used as a drug instead of a nutrient?

I had a college acquaintance who essentially did the same thing with over-the-counter laxatives from the pharmacy in order to fit into her skinny jeans before a big party!

Ascorbate Cleanse Benefits?

Detoxification with high doses of ascorbic acid will quickly resolve any vitamin C deficiency that exists.

That is the only benefit I can identify from this natural remedy. Whether it is worth the stress and strain of forcing a rapid and violent excretory response is doubtful!

I can report that in two decades of raising 3 children, I have never found the need to use this type of flush for any reason.

There are simply too many other options that accomplish the same thing much more gently!

Forcing violent diarrhea on yourself let alone a child seems excessive!

Vitamin C Flush Risks

Warning: Some people get a migraine-like headache from ingesting large amounts of plain ascorbic acid in such a short period of time.

An ascorbic acid-induced headache can last for 1-2 days and does not easily respond to over-the-counter pain medication. It can be quite debilitating.

Bloating and a flare-up of hemorrhoids after a flush are potential side effects as well.

Whole food vitamin C does not typically cause the same problem. In fact, it’s much harder to accomplish an ascorbate flush using whole food vitamin C.

This is because the ascorbic acid is bound with synergistic co-factors not present in plain ascorbic acid. These substances have a mitigating effect on the violent detoxification response.

They also allow you to take far fewer milligrams per day to achieve optimal vitamin C status

Doesn’t this tell you something right there?

Whole Vitamin C Compared to Ascorbic Acid

Here are some of the best whole food vitamin C products on the market and how much real ascorbic acid each contains.

For reference, 1/2 tsp of plain ascorbic acid powder contains roughly 2,500 mg of synthetically derived Vitamin C.

Compare to these whole food sources of L-ascorbic acid (whole Vitamin C complex) below.

  • Pure Radiance Whole Food Vitamin C: 1/2 tsp contains 240 mg natural L-ascorbic acid
  • Organic Acerola Powder (no additives): 1/2 tsp contains 240 mg natural L-ascorbic acid
  • Royal Camu Powder Whole Food Vitamin C:  1/2 tsp contains 100 mg natural L-ascorbic acid
  • Premier Whole Food Vitamin C: 1/2 tsp contains 40 mg natural L-ascorbic acid

As you can see, the plain ascorbic acid powder is a minimum of 10 times more potent than the best whole food vitamin C supplements on the market!

Why is isolated ascorbic acid so different from whole food vitamin C?

The reason is that it is synthetic at best and GMO at worst!

Isolated ascorbic acid powder must be made in a factory. This includes liposomal Vitamin C, much touted in the alternative community. I personally avoid it.

Whole vitamin C from food always comes with synergistic substances that enhance its many benefits. Using plain ascorbic acid or ascorbate to do rapid detoxification is indeed like using a drug.

GMO Vitamin C

Another problem is ascorbic acid from a genetically modified source. GMO corn is the usual culprit. If this is the case, then the risk of ingesting glyphosate residue is very real.

The residue exposure is very small, to be sure, but if you have the choice to not consume it and use a nonGMO whole food Vitamin C, then why not? Glyphosate is a suspected carcinogen and at the very least, damages beneficial gut flora even in minute amounts.

The EU Parliament recently voted to ban it by 2022. The UK is considering a similar measure. (1)

Conventional farmers, if you recall, heavily and repeatedly spray GMO crops with Roundup. They are genetically modified to withstand the onslaught of the herbicide as they are “Roundup Ready”.

It’s true that dozens of nonGMO crops like wheat are sprayed with Roundup too (primarily for desiccation purposes just prior to harvest). However, conventional farms douse GMO corn, soy, sugar beets, and canola much more heavily and repeatedly.

Health Risks from High Dose Ascorbic Acid

While a Vitamin C flush is a short-term process, there are many folks who get somewhat addicted to the detoxifying effects that are so easily achieved. Hence the popularity of those Emergen-C packets which are available everywhere now – even at gas stations!

Beware!

500+ mg of plain ascorbic acid a day may increase the risk for arterial plaque buildup. Another study showed that people taking ascorbic acid supplements may be more prone to gallstones. Although ascorbic acid was discovered in the 17th century and is critical to human health, its complete role still remains a mystery with many contradictions in the research studying its beneficial health effects! (2)

The bottom line is that it’s best to stick with natural, whole food forms of vitamin C. Avoid high doses of isolated ascorbic acid or buffered ascorbic acid (ascorbate) devoid of beneficial co-factors.

Alternatives to a Vitamin C Flush

There is no doubt that detoxification helps with healing and recovery from illness. However, forcing the issue with megadoses of synthetic vitamin C does not seem wise.

Here are 4 suggestions for safer detoxification options. They will work just as well as a vitamin C flush without the violent intestinal response!

  • Epsom Salt Baths: Epsom salt is magnesium sulfate crystals. Soaking the feet or the entire body in a warm bath with a small number of Epsom salts added will gently encourage elimination without stress and strain. In fact, any regular program of detoxification bathing would be helpful. Be sure to buy the best Epsom salt by looking for proper labeling.
  • Coffee Enemas: The word “enema” is a repulsive word for some. However, the process is ancient and the detoxification results are profound. See the linked article for more detail. If using an enema bag is off-putting, ready to use, saline enema bottles are available for just a few dollars at the pharmacy. Be sure to get a brand without chemical additives.
  • Castor Oil Pack: Oral castor oil is another way to invoke a violent diarrhea response similar to a vitamin C flush. Sometimes pregnant women use it to start labor without induction drugs (not recommended!). When used externally on the abdomen, however, the results are gentle but still very effective.
  • Cleansing Herbs: A simple detox tea (this one is very effective) can gently invoke an elimination response without violent diarrhea.

Therapeutic Uses for High Dose Vitamin C

We’ve established that using high-dose vitamin C for basic detoxification in otherwise healthy people may not be such a great idea.

If a person is gravely ill with few options for recovery, however, high dose vitamin C therapy especially intravenously can prove helpful.

Cancer Therapy

For example, emerging evidence is that high doses of ascorbic acid or ascorbate can play an important role in holistic cancer therapies. (2) 

High doses of C are useful in conjunction with conventional treatment. For example, researchers have already published research concerning how ascorbate/ascorbic acid effectively fights tumor cells.

Removal of Amalgams

It is also helpful to use intravenous Vitamin C to detox after removal of mercury amalgams.

In this instance, the Vitamin C ensures that any mercury that gets loose in the bloodstream during the removal of the silver fillings is hastened to the excretory system before it can get deposited for storage in the fat cells.

Situations like these are examples where high dose vitamin C treatment can prove helpful. However, it is important not to jump on the bandwagon for routine illnesses especially where children are concerned.

While high dose vitamin C definitely has its place as holistic therapy for the critically ill, healthy people simply seeking to detox should use it with caution.

Fast is not necessarily better, which is why I’ve always said “no” to this natural remedy.

woman dropping high dose vitamin c tablet in water

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Category: Detoxification, Natural Remedies
Sarah Pope

Sarah Pope MGA has been a Health and Nutrition Educator since 2002. She is a summa cum laude graduate in Economics from Furman University and holds a Master’s degree from the University of Pennsylvania.

She is the author of three books: Amazon #1 bestseller Get Your Fats Straight, Traditional Remedies for Modern Families, and Living Green in an Artificial World.

Her four eBooks Good Diet…Bad Diet, Real Food Fermentation, Ketonomics, and Ancestrally Inspired Dairy-Free Recipes are available for complimentary download via Healthy Home Plus.

Her mission is dedicated to helping families effectively incorporate the principles of ancestral diets within the modern household. She is a sought after lecturer around the world for conferences, summits, and podcasts.

Sarah was awarded Activist of the Year in 2010 at the International Wise Traditions Conference, subsequently serving on the Board of Directors of the nutrition nonprofit the Weston A. Price Foundation for seven years.

Her work has been covered by numerous independent and major media including USA Today, ABC, and NBC among many others.

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Reader Interactions

Comments (56)

  1. Mike

    Mar 17, 2018 at 12:18 pm

    I’ve found it works well to alleviate diverticulitis flare ups.

    Reply
  2. Maria Nikopoulos

    Mar 14, 2018 at 9:17 pm

    High dose vitamin C along with l lysine and l proline is used to heal arteries and prevent arterial build up. Many people have healed their blocked arteries in this manner. Kindly educate yourself on the works of Linus Pauling before turning people away from a protocol that can save their life.
    Be well

    Reply
  3. Sarah

    Dec 15, 2017 at 5:53 am

    So Vitamin C flush is not a good idea unless you’re sick because it causes explosive bowels, MIGHT contain GMO’s (buy GMO free) and people can get addicted? But sticking coffee in our bowels to clear the colon is a safer recommendation? This is why most ppls don’t have the education or are qualified to advise on such topics.
    -Unlike most mammal species, humans don’t synthesize Vitamin C on their own. We lost that ability when we no longer had the enzyme to do so.
    -Vitamin C helps the body deal with stress due to aiding in the synthesis of hormone production. Stress utilizes high amounts of Vitamin C and quickly depletes the body of t, so anyone who deals with some stress can problably benefit.
    -Vitamin C helps repair the adrenals
    -Vitamin C helps with the production of other antioxidants that are extremely important such as glutathione.
    -Vitamin C has been shown to potentially help with weight loss
    -Vitamin C aides in the production of collagen

    And there’s much more…

    I wouldn’t underestimate a Vitamin C flush. Also, it pretty much has an enema-like effect and is no more harsh on the bowel. It’s actually a very easy release. I’m guessing you didn’t try it? Coffee enemas have more risk factors and precautions.

    Reply
    • Sarah

      Dec 15, 2017 at 9:09 am

      If you are so in love with Vitamin C flushes .. then go ahead and do them! 🙂

  4. steve b

    Dec 4, 2017 at 11:21 pm

    i normally agree w/you but not sure on this one…i listened to dr. rusell jaffee(sp) and he explained how using the right kind of vitamin c like you said enables you to get the amount of vitamin c your body needs for tissue repair and isnt getting. it is different for everybody and many people need a lot more than you mention. and i mean a lot more. the flush sets the level for the daily amount you need and over time as you achieve repair you level off. vit c is the only substance that supposedly removes all toxins as well. maybe it is a better thing for people who dont have ideal health but most people are not getting enough.

    Reply
  5. Melanie

    Nov 26, 2017 at 4:56 pm

    Sarah, What is your opinion of taking non-gmo (not made in china) vitamin c daily, not as a flush but as a daily supplement?

    Reply
    • Sarah

      Nov 26, 2017 at 8:39 pm

      If it’s whole food vitamin C, that is fine.

  6. Marksechs

    Nov 21, 2017 at 7:22 am

    The man taking high dose vitamin c for 60 years won two noble prizes. He died at the age of 93. His name is Linus Carl Pauling.

    Reply
    • Sarah

      Nov 21, 2017 at 11:27 am

      N=1 doesn’t mean much. Also … there was no GMO vitamin C when he was alive.

  7. Althea Dease

    Nov 19, 2017 at 7:20 am

    Even more important use for Powdered Vit C, even Emergency C packets, is for burns. Did you touch that metal rack in the oven while pulling out the pan? Open that vitamin C powder, sprinkle it liberally on a damp paper towel and wrap it around that burn. Keep it there for 5 -10 minutes. Pain gone, sensitivity to hot water gone! All the gymnasts at my YMCA, sprinkle that C powder on their hands before they wrap them to keep from getting friction burns when they do the bars. But with all the burns I have gotten cooking, I do not have a single scar. And as a preschool teacher, take that Vit C (1,000 to 10,000 mg) when the word Rotovirus hits your ears and you will be grateful for Linus Pauling and Adele Davis…..

    Reply
    • Sarah

      Nov 19, 2017 at 10:31 am

      This is what I use for burns and it is very effective. Much more convenient … you don’t have to wrap it. Just rub it on immediately. https://www.thehealthyhomeeconomist.com/all-purpose-comfrey-salve-recipe/

  8. Victoria Stokes

    Nov 13, 2017 at 12:49 am

    It occurred to me that cold’s come in winter or if caught in a draught – in other words, colds love cold. In Summer we often overheat and as uncomfortable as this can be we don’t get colds. This winter I made sure if I started to get over cool to overheat for a short time afterwards. No cold all winter and I’m 70. Love to hear if anyone else has tried this

    Reply
  9. Rebecca

    Nov 11, 2017 at 10:54 am

    High dose Vitamin C is best done with a liposomal Vitamin C which bypasses the gut altogether and provides a similar benefit as high dose intravenous Vitamin C. This can be a very successful remedy to stopping a cold in its tracks without any of the uncomfortable side effects of diarrhea. I recommend people doing their own research on liposomal Vitamin C – it is superior to ascorbic acid, in my opinion, and provides GREAT benefit.

    Reply
  10. Yoga monkey

    Nov 11, 2017 at 3:39 am

    What a load of rubbish. I suggest you educate yourself correctly and open your eyes to the amazing healing effects of high dose Vitamin C. After all we are only emulating most other mamals who manufacture their own Ascorbic Acid. They don’t manufacture Whole food C! The main purpose of the flush is simply to find your bowel tolerance as everyone is different. Then the correct dose can be maintained. Spreading this dis-information is depriving many people of the wonderful healing potential of therapeutic dose vitamin C.

    Reply
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