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Healthy Home Economist / Archives / Natural Remedies / Peer-Reviewed Study: Cod Liver Oil Reduces Rheumatoid Arthritis Symptoms

Peer-Reviewed Study: Cod Liver Oil Reduces Rheumatoid Arthritis Symptoms

by Sarah Pope / Affiliate Links ✔

Table of Contents[Hide][Show]
  • Cod Liver Oil Reduces RA Symptoms+−
    • Cod Liver Oil Chosen Over Fish Oil
    • How Long Until Improvement?
  • Conclusions

Peer-reviewed study reports that daily consumption of the age-old remedy cod liver oil for 24 weeks is statistically significant at reducing Rheumatoid Arthritis pain and the use of NSAID drugs like ibuprofen to manage symptoms.

woman taking cod liver oil with less pain in her left hand

Rheumatoid Arthritis can be an extremely painful as well as disabling illness. As a result, those suffering from this autoimmune disease frequently find themselves relying on non-steroidal anti-inflammatory drugs (NSAIDs). Examples include Voltaren (diclofenac sodium) and ibuprofen that provide relief in order to function on a daily basis.

The problem is that NSAIDs are associated with an increased risk of serious cardiovascular events, myocardial infarction, and stroke. This risk further escalates with a longer duration of use and at larger dosages.

In addition, those who already have cardiovascular disease or risk factors are likely at greater risk for a potentially fatal cardiovascular event.

Consequently, limiting NSAID use and minimizing dosage are very important goals in the management of Rheumatoid Arthritis (RA).

The good news is that the results of a peer-reviewed study suggest that it is indeed possible to reduce dependence on NSAIDs for Rheumatoid Arthritis with the help of the old fashioned cod liver oil.

The pilot study, reported in the Journal of Clinical and Diagnostic Research, involved 30 Rheumatoid Arthritis patients aged 19 to 60 years. (1)

Cod Liver Oil Reduces RA Symptoms

Each patient received 1.5 grams of cod liver oil twice each day given as five, 300 mg capsules. The cod liver oil regimen continued for a period of 24 weeks.

Note that while helpful, the benefits of krill oil do not outweigh those of cod liver oil. Hence, this supplement is not an adequate substitute.

The omega-3 fatty acid content of each capsule was Eicosapentaenoic acid (EPA) 20 mg and Docosahexaenoic acid (DHA) 30 mg. The fat-soluble vitamin content of each capsule was Vitamin A-284 IU and Vitamin D-28.4 IU.

Hence, the total dosage each day from the 10 capsules (5 taken twice daily) was EPA-200 mg, DHA-300 mg, Vitamin A-2840 IU, and Vitamin D-284 IU.

Cod Liver Oil Chosen Over Fish Oil

It is important to note that the study authors chose cod liver oil over plain fish oil. The reason is that unprocessed cod liver oil contains natural Vitamins A and D. Plain fish oil is highly processed and does not contain these critical fat-soluble nutrients.

Vitamin A protects against liver damage from Methotrexate therapy, a mainstay in the treatment of Rheumatoid Arthritis. Cod liver oil is also protective against Vitamin D deficiency which is highly prevalent in the disease. (2)

In addition to the cod liver oil, the patients took 50 mg of Diclofenac Sodium in a single daily dose with the maximum allowed NSAID dose of 200 mg/day.

How Long Until Improvement?

The average daily NSAID requirement for each patient was recorded and compared throughout the 24 week period. In addition, the pain score of the patients was evaluated using the Visual Analogue Scale (VAS) at different weeks. In addition, researchers assessed patient “Subjective Response” to Rheumatoid Arthritis pain.

Administration of the cod liver oil over the 24 week period resulted in a statistically significant decrease in the mean VAS pain score from 80.38 ± 6.4 at the beginning of the study to 67.30 ± 5.3 at its conclusion.

Even more encouraging, the percentage of patients who experienced a subjective response assessment of “Better” increased dramatically from 15.38% at week 4 to 61.53% at week 24.

Conclusions

The authors of the study concluded the following:

This study revealed that the concurrent use of cod liver oil which contained n-3 Essential Fatty Acid in Rheumatoid Arthritis patients reduced the mean daily dose of Diclofenac Sodium consumed and probably the incidence of the side effects which were associated with it.

Given that cod liver oil is a safe remedy used for centuries even as far back as Viking and Roman times. Thus, it would seem reasonable to try it for 5-6 months as the patients did in this study. Dosage for this length of time may result in a significant improvement in symptoms and reduction in NSAID dependence.

These brands of cod liver oil are completely unprocessed for maximum results. I personally prefer to use cod liver oil sourced from Iceland at the present time because of the purity of the ocean in that part of the world.

Below is a short video where I explain the study and results for those of you that prefer a visual medium.

woman taking cod liver oil with arthritis in her left hand

References

(1) J Clin Diagn Res. 2013 July; 7(7): 1347—1351
(2) Beta Carotene Mitigages Methotrexate–Induced Oxidative Liver Damage

More Information

Cod Liver Oil Helps Resolve Night Blindness
Tylenol the Cause of Autoimmune Symptoms in Children?

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Category: Natural Remedies
Sarah Pope

Sarah Pope MGA has been a Health and Nutrition Educator since 2002. She is a summa cum laude graduate in Economics from Furman University and holds a Master’s degree from the University of Pennsylvania.

She is the author of three books: Amazon #1 bestseller Get Your Fats Straight, Traditional Remedies for Modern Families, and Living Green in an Artificial World.

Her four eBooks Good Diet…Bad Diet, Real Food Fermentation, Ketonomics, and Ancestrally Inspired Dairy-Free Recipes are available for complimentary download via Healthy Home Plus.

Her mission is dedicated to helping families effectively incorporate the principles of ancestral diets within the modern household. She is a sought after lecturer around the world for conferences, summits, and podcasts.

Sarah was awarded Activist of the Year in 2010 at the International Wise Traditions Conference, subsequently serving on the Board of Directors of the nutrition nonprofit the Weston A. Price Foundation for seven years.

Her work has been covered by numerous independent and major media including USA Today, ABC, and NBC among many others.

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Reader Interactions

Comments (95)

  1. Jessica Carter Kingsborough via Facebook

    Dec 27, 2013 at 12:29 pm

    CLO helps with systemic inflammation that can also lead to the heart disease associated with Rheumatoid Arthritis. My doctor also recommends turmeric as a supplement.

    Reply
  2. Keely Stewart via Facebook

    Dec 27, 2013 at 12:15 pm

    Cathy Greene

    Reply
  3. Aubrie Granata Pike via Facebook

    Dec 27, 2013 at 11:56 am

    Brianna Miller-Awve… Just a little something to read. What the hell else you have to do right now anyway?! 😉

    Reply
  4. Nichelle Ferreyra via Facebook

    Dec 27, 2013 at 11:51 am

    Thanks…I will pass this on!

    Reply
  5. Reanna Santero via Facebook

    Dec 27, 2013 at 11:46 am

    Nichelle Ferreyra for your friend. Maybe fermented cod liver oil would be better

    Reply
  6. Laura Duvall Huckins via Facebook

    Dec 27, 2013 at 11:45 am

    Larry Duvall

    Reply
  7. Marlo Pabst Hughen via Facebook

    Dec 27, 2013 at 11:35 am

    To my knowledge fermented cod liver oil is only sold by Green Pastures. I take a TSP daily (more than this article says) and still suffer from arthritic pain. I do not take additional NSAID though.

    Reply
    • Ina

      Dec 27, 2013 at 1:15 pm

      Try eliminating all gluten, especially North American Hybrid Wheat. See http://www.thedr.com/index.php as one place to start. It takes 3 months for all the reactions to clear, but you should notice a difference in a week or two. Some people initially feel like they have the flu for the first week or so, hang in there. Also sugar is very inflammatory.

    • Heather

      Jan 29, 2014 at 4:22 pm

      Being gluten free for a year did nothing to help reduce my stiffness and inflammation. I’m sure it helps some but it’s definitely not a cure all.

  8. Tisha Hartman via Facebook

    Dec 27, 2013 at 11:35 am

    This is very true for me. It helps for fibromyalgia pain and headaches as well. I notice such a difference when I’m not on top of it.

    Reply
  9. Lisa Zielke Hubbard via Facebook

    Dec 27, 2013 at 11:32 am

    Shannon

    Reply
  10. Lani A. Wolf via Facebook

    Dec 27, 2013 at 11:30 am

    Where can I the fermented cod liver oil capsules from the safe fish in Russia?

    Reply
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