Why some types of coffee should be avoided by those with Celiac disease or gluten sensitivity, as they contain cross-reactive proteins that can trigger the same inflammatory response.

If you drink coffee and have gluten sensitivity or Celiac disease, be aware that this hot beverage can worsen symptoms.
Even bulletproof coffee can trigger problems.
There is a surprising connection between gluten and coffee that is, by and large, ignored by the health community.
This revelation holds ramifications for other autoimmune disorders as well.
The problem has nothing to do with caffeine, so decaf coffee would be included in this discussion.
In a nutshell, lab research has revealed that 10% of coffee is a protein that cross-reacts with gluten antibodies.
This means that if you are gluten sensitive or Celiac and are avoiding gluten-containing grains or perhaps have even gone completely grain-free…if you still drink coffee, there is a strong likelihood that the protein in the coffee is triggering the very same gluten-related health problems you are trying to avoid.
In other words, even if you think you are doing fine with your current gluten-free diet, it is very possible that skipping the coffee could take your health to the next level.
Symptoms of Gluten Sensitivity
Most people who are gluten sensitive don’t realize it because gastrointestinal problems like burping, gas, tummy upset, or toilet issues are the least common way for gluten issues to present themselves!
The most common symptoms of gluten sensitivity are actually migraines and other neurological issues – even MS!
Hormone and endocrine problems are another common way for gluten issues to manifest themselves.
How Coffee Triggers Autoimmunity
So what exactly happens when a gluten sensitive person eats gluten?
Folks with gluten antibodies react to any gluten in the diet by mounting an immune response.
This means that gluten is perceived by the body as an invader and the gluten antibodies attack the gluten itself trying to destroy it.
This gluten attack is an inflammatory response that can occur anywhere in the body and in any tissue or organ.
Here’s the real shocker I came across when researching the coffee/gluten connection:
According to Dr. David Clark DC, functional neurologist and endocrinologist:
There’s not a disease or health condition you can think of that does not have an association – in the research literature – with gluten sensitivity.
That’s a very strong statement!
In essence, if you are gluten sensitive in any way, shape or form, gluten antibodies have the potential to react to proteins in other foods, triggering an immune and inflammatory response.
The protein in coffee is the most common cross-reactor to gluten.
Because it is the protein in the coffee that is the trigger, switching to decaf coffee does not solve the problem.
Worst Types of Coffee for Gluten Sensitive/Celiacs
Is it possible to be gluten sensitive or Celiac and not cross-react to coffee?
Yes, it’s possible, but you may need to do some expensive lab testing to find out for sure. (1)
If you prefer not to shell out of your own pocket for this type of testing (insurance likely will not cover it), avoiding coffee is the easiest route to go! The good news is that skipping coffee saves adrenal health too!
If you choose to drink coffee anyway, research published in the Journal of Food and Nutrition Sciences has identified the worst offenders for coffee cross-reactivity with gluten: (2)
- Instant coffee
- Preground coffee
The “Good Stuff”
According to Primal Body, Primal Mind author Nora Gedgaudas CNS, CNT, if you are gluten sensitive or Celiac, it is very important to drink the “good stuff” if you choose to drink coffee at all.
This means buying organic roasted coffee beans and grinding them yourself to make a cuppa at home!
Definitely skip the Starbucks drive-through and other coffee vendors where the quality is unknown or suspect.
References
(1) Cyrex Labs
(2) Cross-Reaction between Gliadin and Different Food and Tissue Antigens, Journal of Food and Nutrition Sciences
More Information
You Probably Need to Change WHEN You Drink Coffee
Coffee Enema
Morning Coffee Fix
Caffeine and Chronic Back Pain
Healthy Coffee Substitutes
What about coffee enemas? Gluten-sensitive people shouldn’t have that?
If you do them, follow the guidelines in the article for finding the best type of coffee with the least chance of cross-reaction.
Unlike many people, my main symptom when ingesting gluten is tachycardia. But even on a gluten-free diet, I would have episodes. Since I stopped drinking coffee, they have become rare. It isn’t caffeine because I have no issues whatsoever with tea.
Where’s the research article, so that I can read through it?
7. Do I have to give up coffee and corn on a gluten-free diet?
No, coffee and corn are both gluten-free. There is no scientific evidence to show that coffee or corn contain proteins that cross-react with gluten. According to Dr. Stefano Guandalini, a CDF Medical Advisory Board member, both are safe for people with celiac disease to consume.
From celiac.org I’m confused. Lots of other resources say otherwise.
listen to your body. maybe try cutting out coffee for a while, and then testing it again
What other foods cross react to gluten? I’m celiac & I can’t drink coffee anymore.
Recently diagnosed and grateful to find this article. This is one of my culprits. I realized my salad dressing was and after changing diet and drinking coffee dairy free I noticed immediately it was affecting me. Right after I drink and throughout the day with joint pain. Thank you
The issue with being celiac or gluten sensitive is that the effects from eating gluten are longterm. Also many people with celiac/a gluten sensitivity said that they were fine with 1-2 cups a morning but when they drank more they would start to feel sick so if you do decide to take the risk by drinking coffee I suggest you limit it to one cup of coffee per day. Be careful!
Many thanx – I guzzle coffee – I have problems with inflammation though massively less than when I used to eat gluten containing foods – but I think I’ll stop coffee which would be a miracle after reading your article.
: )