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Healthy Home Economist / Archives / Healthy Living / Gluten Sensitivity or Celiac? Beware of Coffee!

Gluten Sensitivity or Celiac? Beware of Coffee!

by Sarah Pope / Updated: Aug 14, 2025 / Affiliate Links ✔

Table of Contents[Hide][Show]
  • Symptoms of Gluten Sensitivity
  • How Coffee Triggers Autoimmunity
  • Worst Types of Coffee for Gluten Sensitive/Celiacs
  • The “Good Stuff”

Why some types of coffee should be avoided by those with Celiac disease or gluten sensitivity, as they contain cross-reactive proteins that can trigger the same inflammatory response.

white cup of coffee for a person with Celiac

If you drink coffee and have gluten sensitivity or Celiac disease, be aware that this hot beverage can worsen symptoms.

Even bulletproof coffee can trigger problems.

There is a surprising connection between gluten and coffee that is, by and large, ignored by the health community.

This revelation holds ramifications for other autoimmune disorders as well.

The problem has nothing to do with caffeine, so decaf coffee would be included in this discussion.

In a nutshell, lab research has revealed that 10% of coffee is a protein that cross-reacts with gluten antibodies.

This means that if you are gluten sensitive or Celiac and are avoiding gluten-containing grains or perhaps have even gone completely grain-free…if you still drink coffee, there is a strong likelihood that the protein in the coffee is triggering the very same gluten-related health problems you are trying to avoid.

In other words, even if you think you are doing fine with your current gluten-free diet, it is very possible that skipping the coffee could take your health to the next level.

Symptoms of Gluten Sensitivity

Most people who are gluten sensitive don’t realize it because gastrointestinal problems like burping, gas, tummy upset, or toilet issues are the least common way for gluten issues to present themselves!

The most common symptoms of gluten sensitivity are actually migraines and other neurological issues – even MS!

Hormone and endocrine problems are another common way for gluten issues to manifest themselves.

How Coffee Triggers Autoimmunity

So what exactly happens when a gluten sensitive person eats gluten?

Folks with gluten antibodies react to any gluten in the diet by mounting an immune response. 

This means that gluten is perceived by the body as an invader and the gluten antibodies attack the gluten itself trying to destroy it.  

This gluten attack is an inflammatory response that can occur anywhere in the body and in any tissue or organ.

Here’s the real shocker I came across when researching the coffee/gluten connection:

According to Dr. David Clark DC, functional neurologist and endocrinologist:

There’s not a disease or health condition you can think of that does not have an association – in the research literature – with gluten sensitivity.

That’s a very strong statement!

In essence, if you are gluten sensitive in any way, shape or form, gluten antibodies have the potential to react to proteins in other foods, triggering an immune and inflammatory response.

The protein in coffee is the most common cross-reactor to gluten.

Because it is the protein in the coffee that is the trigger, switching to decaf coffee does not solve the problem.

Worst Types of Coffee for Gluten Sensitive/Celiacs

Is it possible to be gluten sensitive or Celiac and not cross-react to coffee? 

Yes, it’s possible, but you may need to do some expensive lab testing to find out for sure. (1)

If you prefer not to shell out of your own pocket for this type of testing (insurance likely will not cover it), avoiding coffee is the easiest route to go! The good news is that skipping coffee saves adrenal health too!

If you choose to drink coffee anyway, research published in the Journal of Food and Nutrition Sciences has identified the worst offenders for coffee cross-reactivity with gluten: (2)

  • Instant coffee
  • Preground coffee

The “Good Stuff”

According to Primal Body, Primal Mind author Nora Gedgaudas CNS, CNT, if you are gluten sensitive or Celiac, it is very important to drink the “good stuff” if you choose to drink coffee at all.

This means buying organic roasted coffee beans and grinding them yourself to make a cuppa at home!

Definitely skip the Starbucks drive-through and other coffee vendors where the quality is unknown or suspect.

References

(1) Cyrex Labs

(2) Cross-Reaction between Gliadin and Different Food and Tissue Antigens, Journal of Food and Nutrition Sciences

More Information

You Probably Need to Change WHEN You Drink Coffee
Coffee Enema
Morning Coffee Fix
Caffeine and Chronic Back Pain
Healthy Coffee Substitutes

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Category: Healthy Living
Sarah Pope

Sarah Pope MGA has been a Health and Nutrition Educator since 2002. She is a summa cum laude graduate in Economics from Furman University and holds a Master’s degree from the University of Pennsylvania.

She is the author of three books: Amazon #1 bestseller Get Your Fats Straight, Traditional Remedies for Modern Families, and Living Green in an Artificial World.

Her four eBooks Good Diet…Bad Diet, Real Food Fermentation, Ketonomics, and Ancestrally Inspired Dairy-Free Recipes are available for complimentary download via Healthy Home Plus.

Her mission is dedicated to helping families effectively incorporate the principles of ancestral diets within the modern household. She is a sought after lecturer around the world for conferences, summits, and podcasts.

Sarah was awarded Activist of the Year in 2010 at the International Wise Traditions Conference, subsequently serving on the Board of Directors of the nutrition nonprofit the Weston A. Price Foundation for seven years.

Her work has been covered by numerous independent and major media including USA Today, ABC, and NBC among many others.

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Reader Interactions

Comments (438)

  1. wisdom, wine and wild daffodils via Facebook

    Oct 6, 2012 at 4:09 pm

    I heard of this potential connection a few months back but I then soon after heard some evidence contradicting it by a well-reputed source whom I can not just now remember precisely (may have been Chris Kresser but will try to find it and confirm). I must do some digging further on this issue. I’m not sure what to make of it but caution and monitoring how one feels is probably a wise idea.

    Reply
  2. Raine Irving Saunders via Facebook

    Oct 6, 2012 at 4:08 pm

    There are so many things like this that cause issues for people with celiac or gluten sensitivity that a lot of people don’t think about. I was working with one of my GAPS clients the other day and she said she had completely gone off grains but was still having problems. She doesn’t want to give up coffee, although I encouraged her to do so or at least cut back to a great extent. We ran through all the possibilities of other foods she might be eating that are causing problems and she mentioned balsamic vinegar and I said, “bingo!” Then she said, “wow, I eat it probably several times a day because I love it so much! No wonder I am still having problems.” She didn’t know this usually contains gluten.

    Reply
  3. Lauren Simons via Facebook

    Oct 6, 2012 at 3:59 pm

    Ps- I don’t drink coffee. I gave it up for caffeine.

    Reply
  4. Lauren Simons via Facebook

    Oct 6, 2012 at 3:58 pm

    I think its a load of crap. Coffee & gluten aren’t related unless someone puts some sort of wheat ( or other gluteneous grain) in their coffee blend.

    Reply
  5. Faith Harron Boudreau via Facebook

    Oct 6, 2012 at 3:55 pm

    I was coffee free for 2 weeks earlier this year – while detoxing a bit. I felt pretty good once I was past the withdrawal of caffeine. I thought by drinking decaf I was safe. Maybe not. I have been drinking less – so maybe now is the time to give it up completely. Or when I run out of the 3 bags in my pantry.

    Reply
  6. Jennifer Starmann via Facebook

    Oct 6, 2012 at 3:52 pm

    Love your blog, but you just ruined my day. Boo.

    Reply
  7. Laura Matula via Facebook

    Oct 6, 2012 at 3:47 pm

    NaomiBell, did you know this? I didn’t.

    Reply
  8. Kati Stiles Carter via Facebook

    Oct 6, 2012 at 3:45 pm

    I love coffee but haven’t had it for over a year because of how it makes me feel. I thought it was the caffeine, but tea doesn’t affect me like coffee at all.

    Reply
  9. Katie Marie via Facebook

    Oct 6, 2012 at 3:42 pm

    Oh no!

    Reply
  10. Elizabeth Nicholson via Facebook

    Oct 6, 2012 at 3:40 pm

    Do you think the same rule would apply to chocolate since it is also a bean?

    Reply
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