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Healthy Home Economist / Archives / Healthy Living / Gluten Sensitivity or Celiac? Beware of Coffee!

Gluten Sensitivity or Celiac? Beware of Coffee!

by Sarah Pope / Updated: Aug 14, 2025 / Affiliate Links ✔

Table of Contents[Hide][Show]
  • Symptoms of Gluten Sensitivity
  • How Coffee Triggers Autoimmunity
  • Worst Types of Coffee for Gluten Sensitive/Celiacs
  • The “Good Stuff”

Why some types of coffee should be avoided by those with Celiac disease or gluten sensitivity, as they contain cross-reactive proteins that can trigger the same inflammatory response.

white cup of coffee for a person with Celiac

If you drink coffee and have gluten sensitivity or Celiac disease, be aware that this hot beverage can worsen symptoms.

Even bulletproof coffee can trigger problems.

There is a surprising connection between gluten and coffee that is, by and large, ignored by the health community.

This revelation holds ramifications for other autoimmune disorders as well.

The problem has nothing to do with caffeine, so decaf coffee would be included in this discussion.

In a nutshell, lab research has revealed that 10% of coffee is a protein that cross-reacts with gluten antibodies.

This means that if you are gluten sensitive or Celiac and are avoiding gluten-containing grains or perhaps have even gone completely grain-free…if you still drink coffee, there is a strong likelihood that the protein in the coffee is triggering the very same gluten-related health problems you are trying to avoid.

In other words, even if you think you are doing fine with your current gluten-free diet, it is very possible that skipping the coffee could take your health to the next level.

Symptoms of Gluten Sensitivity

Most people who are gluten sensitive don’t realize it because gastrointestinal problems like burping, gas, tummy upset, or toilet issues are the least common way for gluten issues to present themselves!

The most common symptoms of gluten sensitivity are actually migraines and other neurological issues – even MS!

Hormone and endocrine problems are another common way for gluten issues to manifest themselves.

How Coffee Triggers Autoimmunity

So what exactly happens when a gluten sensitive person eats gluten?

Folks with gluten antibodies react to any gluten in the diet by mounting an immune response. 

This means that gluten is perceived by the body as an invader and the gluten antibodies attack the gluten itself trying to destroy it.  

This gluten attack is an inflammatory response that can occur anywhere in the body and in any tissue or organ.

Here’s the real shocker I came across when researching the coffee/gluten connection:

According to Dr. David Clark DC, functional neurologist and endocrinologist:

There’s not a disease or health condition you can think of that does not have an association – in the research literature – with gluten sensitivity.

That’s a very strong statement!

In essence, if you are gluten sensitive in any way, shape or form, gluten antibodies have the potential to react to proteins in other foods, triggering an immune and inflammatory response.

The protein in coffee is the most common cross-reactor to gluten.

Because it is the protein in the coffee that is the trigger, switching to decaf coffee does not solve the problem.

Worst Types of Coffee for Gluten Sensitive/Celiacs

Is it possible to be gluten sensitive or Celiac and not cross-react to coffee? 

Yes, it’s possible, but you may need to do some expensive lab testing to find out for sure. (1)

If you prefer not to shell out of your own pocket for this type of testing (insurance likely will not cover it), avoiding coffee is the easiest route to go! The good news is that skipping coffee saves adrenal health too!

If you choose to drink coffee anyway, research published in the Journal of Food and Nutrition Sciences has identified the worst offenders for coffee cross-reactivity with gluten: (2)

  • Instant coffee
  • Preground coffee

The “Good Stuff”

According to Primal Body, Primal Mind author Nora Gedgaudas CNS, CNT, if you are gluten sensitive or Celiac, it is very important to drink the “good stuff” if you choose to drink coffee at all.

This means buying organic roasted coffee beans and grinding them yourself to make a cuppa at home!

Definitely skip the Starbucks drive-through and other coffee vendors where the quality is unknown or suspect.

References

(1) Cyrex Labs

(2) Cross-Reaction between Gliadin and Different Food and Tissue Antigens, Journal of Food and Nutrition Sciences

More Information

You Probably Need to Change WHEN You Drink Coffee
Coffee Enema
Morning Coffee Fix
Caffeine and Chronic Back Pain
Healthy Coffee Substitutes

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Category: Healthy Living
Sarah Pope

Sarah Pope MGA has been a Health and Nutrition Educator since 2002. She is a summa cum laude graduate in Economics from Furman University and holds a Master’s degree from the University of Pennsylvania.

She is the author of three books: Amazon #1 bestseller Get Your Fats Straight, Traditional Remedies for Modern Families, and Living Green in an Artificial World.

Her four eBooks Good Diet…Bad Diet, Real Food Fermentation, Ketonomics, and Ancestrally Inspired Dairy-Free Recipes are available for complimentary download via Healthy Home Plus.

Her mission is dedicated to helping families effectively incorporate the principles of ancestral diets within the modern household. She is a sought after lecturer around the world for conferences, summits, and podcasts.

Sarah was awarded Activist of the Year in 2010 at the International Wise Traditions Conference, subsequently serving on the Board of Directors of the nutrition nonprofit the Weston A. Price Foundation for seven years.

Her work has been covered by numerous independent and major media including USA Today, ABC, and NBC among many others.

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Reader Interactions

Comments (438)

  1. Kendall

    Oct 23, 2012 at 2:07 am

    I had tests showing gluten & dairy allergies. Therefore my coffee is black.
    However I always feel terrible after drinking it. Dehydrated, sore joints, dizzy, confused, insomnia, unhappy gut….and basically feeling stressed/jittery. The good feeling at the time of drinking it lasts 10 minutes before the nasty symptoms kick in.
    Probably the strangest symptom is fluid retention, especially under my eyes (kidney/adrenal zone, go figure!).
    I’m grateful for this blog post. It makes a lt of sense to me. I think research in future will confirm all of this.
    By the way – my relative is Celiac, he gets the runs after coffee. Now we know why.
    Finally, I just wanted to say that education doesn’t install fear. Knowledge is empowerment. Yes, more research on this is needed. However Chinese herbs worked & weren’t researched for hundreds of years. Many still haven’t been! Peer reviewed lit is not the be all & end all.

    Reply
  2. Primo Health Coach

    Oct 22, 2012 at 11:38 pm

    I worked at a seminar by Apex Energetics this weekend on Neurotransmitters and Brain. Part of the discussion focused on gluten and its affect on the brain for those that are gluten sensitive. The speaker at this event works closely with Dr. Vojdani from Cyrex Labs. He explained that the coffee tested for in the cross reactive panel is INSTANT COFFEE like Folgers. The speaker explained that Dr. Vojdani also tested gourmet coffees like Starbucks and there were NO cross reactivity issues with these coffees. You may want to update this article given this information.

    Reply
    • Amy

      Aug 9, 2013 at 3:34 pm

      I reacted to Starbucks coffee!

  3. jess

    Oct 17, 2012 at 4:57 pm

    Does tea count too?

    Reply
  4. Arthur

    Oct 12, 2012 at 11:47 pm

    Great website!
    But for the link between coffee and gluten, I am a bit annoyed with the science behind this study.
    Dr.Clark and Dr. Vodjani mention recent medical studies (I presume in April 2012) but unfortunately there is no medical study published in any scientific journal (at least in October 2012) on a direct link between gluten and coffee. You can easily check in PubMed with the keywords ‘Gluten’ and ‘Coffee’ at http://www.ncbi.nlm.nih.gov/pubmed
    There is an article in 1983 indicating that coffee contains peptides that can bind to opioid receptors. Gluten peptides can also bind to opioid receptors. This common point does not suggest that the peptides in the coffee can trigger the same reaction that those in gluten. Many different opioid receptors exist and thus the peptides in coffee and gluten could be very different.
    Besides, revealing results from medical studies before publication is usually a bad idea. Once the data is reviewed by other experts in the field, it can be discovered that it was not reliable. It can be very suspicious to talk about data that have never been scientifically checked.

    That being said I am gluten sensitive and I feel that some coffees are not acting very well on my intestines. Since I observe similar effects with other drinks with high content with caffeine such as energy drinks, I suppose that it could be due to caffeine. But I do not exclude the possibility that these doctors may be right. They just have to seriously prove it.
    My advice is to try to stop coffee for a few weeks and see if there is any improvement on the intestinal health. Another advice if you decide to stop coffee: stop progressively or you may experience bad withdrawal effects such as headaches. Black tea first and then green tea seems to me a good way to go through the transition more smoothly.

    Reply
  5. Si Clark

    Oct 8, 2012 at 12:15 am

    I would really appreciate it if you could cite the scientific research studies supporting “10% of coffee is a protein that cross reacts with gluten antibodies.”
    Chiropractor David C. Clark is not enough.
    Thank you.
    S

    Reply
  6. Lucia Lazar Kocak via Facebook

    Oct 7, 2012 at 4:32 pm

    very interesting

    Reply
  7. Tsenka Alexander via Facebook

    Oct 7, 2012 at 11:38 am

    PSALM 104:14,15″….”and bread which strengtheneth man’s heart.”

    Reply
  8. Tsenka Alexander via Facebook

    Oct 7, 2012 at 11:27 am

    Blah,blah,blah!!!!!Gluten is actually a splendid complex vegetable protein,which could be transformed to become easily digestible,nutritiuos and delicious via ancient culinary practices which stimulate the innate enzyme activity,as well as neutralize naturally occurring,unwanted anti-nutrients.FERMENTATION,GUYS, THE SLOOOOOOOW KITCHEN!!! K U D O S, S A N D O R E L L I X K A T Z!

    Reply
  9. Nathalie Farquet via Facebook

    Oct 7, 2012 at 11:25 am

    and what about tea? at least, tea leaves are not beans…

    Reply
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